منابع مشابه
The interaction of barbiturates and analeptics.
The interaction of pentobarbitone sodium with three analeptics viz. micoren, pentylenetetrazol and methedrine was studied in mice. Micoren prolonged pentobarbitone sleeping time. pentylenetetrazol shortened the sleeping time. Methedrine also shortened the sleeping time, but clonic convulsions of mild to severe intensity were noticed 45-60 minutes after the drug injection.
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متن کاملEffect of analeptics on brain pentobarbital levels and sleeping time in mice.
IN THE treatment of barbiturate poisoning the therapeutic emphasis has shifted from the use of analeptics and efforts at arousal to a regimen of physiologic supportive therapy.1 For some time, though, analeptics were drugs of choice, the results being transferred from experimental evidenceQ* 3 despite some reports49 5 about the ineffectiveness of these drugs in animals given large doses of barb...
متن کاملEffect of nikethamide (coramine) on incorporation of radioactive phosphate into rat liver deoxypentosenucleic acid.
Examples of substances reported to stimulate liver growth are few. Coramine (nikethamide, or diethylnicotinamide) causes an increase in the absolute, fat-free weight of the liver of the young rat and would appear to qualify as one of these. The effect was first noted by Coulson and Brazda in 1947 (5) in 45-50-gm. rats fed 1.0 per cent levels of Coramine in a high protein diet. It was an un expe...
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ژورنال
عنوان ژورنال: Anaesthesia and Intensive Care
سال: 2018
ISSN: 0310-057X,1448-0271
DOI: 10.1177/0310057x1804600101